Ilse Julia Smolders

The paper demonstrates the use of a photoswitchable cannabinoid, azo-THC-3, to suppress seizures in a mouse model by local photoactivation in the hippocampus, avoiding systemic side effects.

This study demonstrates that photopharmacological activation of A1R reduces seizures in a mouse model of temporal lobe epilepsy with fewer side effects than systemic administration.

The paper characterizes NMU-expressing neurons in the adult mouse brain using a Nmu-Cre knock-in model, revealing a midline modulatory circuit centered on the VMH.

This study identifies a novel anticonvulsant compound that targets neuronal homeostasis by increasing Pumilio expression, showing efficacy in Drosophila and mouse seizure models.