Dimitri De Bundel

The paper demonstrates the use of a photoswitchable cannabinoid, azo-THC-3, to suppress seizures in a mouse model by local photoactivation in the hippocampus, avoiding systemic side effects.

This study uses molecular dynamics simulations to investigate how different ligands affect 5-HT2AR activation, finding that excessive activation causes hallucinations while modest activation may yield antidepressant effects.

This study demonstrates that photopharmacological activation of A1R reduces seizures in a mouse model of temporal lobe epilepsy with fewer side effects than systemic administration.

This study investigates the effect of D2R agonists on fear generalization in male rats and finds no evidence of such an effect.

The paper characterizes NMU-expressing neurons in the adult mouse brain using a Nmu-Cre knock-in model, revealing a midline modulatory circuit centered on the VMH.

The paper investigates whether drug-induced amnesia after reactivating memories through a generalization stimulus (ABB design) shares features with typical reconsolidation interference, showing it depends on prediction error and GluN2B-NMDA receptor activity.