Author

Marcela Moncada‐Vélez

Rockefeller UniversityORCID 0000-0002-3073-5345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alison W. AshbrookiD· 1 shared Ana PinharandaiD· 1 shared Ansgar F. StenzeliD· 1 shared Aurélie CobatiD· 1 shared Avery PeaceiD· 1 shared Brandon S. RazookyiD· 1 shared Carltin SchmidtiD· 1 shared Catherine A. FreijeiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alison W. AshbrookORCID

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1 paper

Recent·Most cited

A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

Jérémie Le Pen, Gabrielle Paniccia, Volker Kinast, Marcela Moncada‐Vélez, Alison W. Ashbrook, Michael Bauer, H.-Heinrich Hoffmann, Ana Pinharanda, Inna Ricardo-Lax, Ansgar F. Stenzel, Edwin A. Rosado-Olivieri, Kenneth H. Dinnon, William C. Doyle, Catherine A. Freije, Seon-Hui Hong, , Charles M. Rice

The paper identifies PLSCR1 as a host factor restricting SARS-CoV-2 entry, which recent variants have evolved to bypass, through a CRISPR screen and integration of genetic studies.

PLoS Biology · Sep 24, 2024Peer-reviewedImmunology