Author

Yuan Liang

University of RochesterORCID 0000-0002-3098-9337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Andrei SeluanoviD· 2 shared Matthew A. SimoniD· 2 shared Seyed Ali BiashadiD· 2 shared Vera A. GorbunovaiD· 2 shared Victoria PaigeiD· 2 shared Alexander TyshkovskiyiD· 1 shared Cheyenne RechsteineriD· 1 shared Denis FirsanoviD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Andrei SeluanovORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 6, 2026

Balance between DNA repair, LINE1 suppression and lifespan in mice with SIRT6 Serine 10 mutations

Zhihui Zhang, Matthew A. Simon, Yuan Liang…·Vera A. Gorbunova

This study shows that SIRT6 Serine 10 mutations in mice affect DNA repair, LINE1 expression, and lifespan, with reduced LINE1 control having a stronger impact on lifespan than enhanced DNA repair.

DOI 10.64898/2026.02.06.704345

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMar 24, 2025

SIRT6 activator fucoidan extends healthspan and lifespan in aged wild-type mice

Seyed Ali Biashad, Eric C. Hillpot, Francesco Morandini…·Vera A. Gorbunova

This study shows that fucoidan, a seaweed-derived polysaccharide, extends healthspan and lifespan in aged mice by activating SIRT6, which reduces LINE1 retrotransposon activity and epigenetic aging.

5 citations

mouseexperimental assay

𝕏 PostBluesky