Author

Zhihui Zhang

Sun Yat-sen University Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Molecular Biology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Alexander TyshkovskiyiD· 1 shared Andrei SeluanoviD· 1 shared Binghe XuiD· 1 shared Caihua Zhang· 1 shared Delun Luo· 1 shared Demeng CheniD· 1 shared Guohui Xu· 1 shared Hailin Yin· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperMolecular Biology

Alexander TyshkovskiyORCID

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3 papers

Recent·Most cited

Self-extending DNA recording with stochastic and programmed writing

Zhihui Zhang, Yingyi Li, Yifang Peng, Rongsong Ling, Kang Li, Maosheng Cheng, Yixin Cheng, Caihua Zhang, Xiaochen Wang, Shuang Chen, Zhenyu He, Demeng Chen

This paper introduces a method for self-extending DNA recording that combines stochastic and programmed writing, enabling the accumulation of cellular histories with joint cellular and tissue readout.

bioRxiv · Oct 16, 2026 · PreprintSynthetic Biology

Balance between DNA repair, LINE1 suppression and lifespan in mice with SIRT6 Serine 10 mutations

Zhihui Zhang, Matthew A. Simon, Yuan Liang, Alexander Tyshkovskiy, Mila Kaplan, Victoria Paige, Seyed Ali Biashad, Vadim N. Gladyshev, Andrei Seluanov, Vera A. Gorbunova

This study shows that SIRT6 Serine 10 mutations in mice affect DNA repair, LINE1 expression, and lifespan, with reduced LINE1 control having a stronger impact on lifespan than enhanced DNA repair.

bioRxiv · Feb 6, 2026 · PreprintMolecular Biology

The plasma miR-122 basal levels respond to circulating catecholamine in rats

Peng Xu, Qiao Li, Song Lu, Xueling He, Sisi Yu, Zhihui Zhang, Guohui Xu, Li Lu, Tinghan Yang, Jiang Zhu, Wenli Zhu, Zhigang Wu, Delun Luo, Jie Zhu, Binghe Xu, , Kai Xu

This study shows that plasma miR-122 levels in rats are influenced by circulating catecholamines and stress, suggesting a non-hepatic source for miR-122 release.

bioRxiv · Jan 31, 2018 · PreprintMolecular Biology