Author

Michael W. Parker

The University of MelbourneORCID 0000-0002-3101-1138Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Larissa DoughtyiD· 2 shared Aditya KrishnakumariD· 1 shared Andrea C. Poblete Goycoolea· 1 shared Andrew FavoriD· 1 shared Angel Francisco LopeziD· 1 shared Ashfaqul HoqueiD· 1 shared Ashley J. OvensiD· 1 shared Belamy B. CheungiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

Larissa DoughtyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 19, 2026

Fine tuning energy metabolism in skeletal muscle: Discovery of a novel autoinhibitory mechanism in the N-terminal extension of AMPKγ3

Ashley J. Ovens, Muhammad N.H. Khabib, Dingyi Yu…·Christopher G. Langendorf

This study identifies an autoinhibitory mechanism in the N-terminal extension of AMPKγ3 that regulates basal activity in skeletal muscle, offering a target for T2DM therapies.

DOI 10.64898/2026.08.16.744724

humanproteomics

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Cancer BiologybioRxivPreprintJul 10, 2026

Therapeutic targeting of MYC- and MYCN-driven medulloblastoma with a novel MYC degrader molecule

Sin Wi Ng, Satyanarayana Gadde, Nga-yee Chung…·Glenn M. Marshall

This study identifies UNSW-SC-22 as a novel MYC/MYCN-targeting molecule that crosses the blood-brain barrier and shows potent preclinical efficacy in medulloblastoma.

DOI 10.64898/2026.07.09.737604

mouseexperimental assay

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Synthetic BiologybioRxivPreprintOct 12, 2025

Geometric Tuning of Cytokine Receptor Association Modulates Synthetic Agonist Signaling

Marc Expòsit, Mohamad H. Abedi, Aditya Krishnakumar…·David A. Baker

This paper designs synthetic cytokine agonists with controlled receptor geometry to modulate signaling outcomes and functional effects.

3 citations

protein structureexperimental assay

𝕏 PostBluesky