Author

Ashfaqul Hoque

St Vincents Institute of Medical ResearchORCID 0000-0003-2384-2983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Ching‐Seng AngiD· 2 shared Alistair Morgan ChalkiD· 1 shared Amardeep S. DhilloniD· 1 shared Andrea C. Poblete Goycoolea· 1 shared Andrew N. ClarksoniD· 1 shared Antoine DufouriD· 1 shared Ashley J. OvensiD· 1 shared Benjamin R. Turner· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Ching‐Seng AngORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 19, 2026

Fine tuning energy metabolism in skeletal muscle: Discovery of a novel autoinhibitory mechanism in the N-terminal extension of AMPKγ3

Ashley J. Ovens, Muhammad N.H. Khabib, Dingyi Yu…·Christopher G. Langendorf

This study identifies an autoinhibitory mechanism in the N-terminal extension of AMPKγ3 that regulates basal activity in skeletal muscle, offering a target for T2DM therapies.

DOI 10.64898/2026.08.16.744724

humanproteomics

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Developmental BiologybioRxivPreprintAug 5, 2025

Deletion of KLHDC3, an E3 ubiquitin ligase complex substrate receptor, leads to obesity in mice.

Paula Armina V. Buco, Ashfaqul Hoque, Wilson Castillo‐Tandazo…·Carl R. Walkley

This study shows that deleting Klhdc3 in mice causes obesity and developmental issues, highlighting its role in regulating protein stability and adiposity.

DOI 10.1101/2025.08.05.668783

mouseproteomics

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NeuroscienceMolecular & Cellular ProteomicsPeer-reviewedApr 6, 2023

N-Terminomic Changes of Neurons During Excitotoxicity Reveal Proteolytic Events Associated with Synaptic Dysfunctions and Inform Potential Targets for Neuroprotection

S. Sadia Ameen, Nane Griem‐Krey, Antoine Dufour…·Heung‐Chin Cheng

The paper identifies proteolytic events in neurons during excitotoxicity using N-terminomics, revealing calpain-mediated cleavage of synaptic proteins and potential therapeutic targets for neuroprotection.

25 citations

ratmouse

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