Cell BiologyAging CellPeer-reviewed
In vivo chemical reprogramming is associated with a toxic accumulation of lipid droplets hindering rejuvenation
Wayne Mitchell, Cecília Gallottini de Magalhães, Alexander Tyshkovskiy…·Vadim N. Gladyshev
This study shows that partial chemical reprogramming in aged mice increases lipid droplet formation, which may cause toxicity and hinder tissue rejuvenation.
3 citations