Author

Juan P. Angel

Rutgers, The State University of New JerseyORCID 0000-0002-3106-9508Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Brian P. DanielsiD· 2 shared Colm AtkinsiD· 2 shared Marissa LindmaniD· 2 shared Aisha P. Patel· 1 shared Diego Alzate· 1 shared Medha Krishnagiri· 1 shared Nydia P. Chang· 1 shared Po-Lun Kung· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Brian P. DanielsORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 24, 2026

SIRT1 remodels astrocyte metabolism and promotes viral replication during neurotropic orthoflavivirus infection

Juan P. Angel, Diego Alzate, Marissa Lindman…·Brian P. Daniels

This study shows SIRT1 promotes viral replication in astrocytes during orthoflavivirus infection by altering metabolism and NAD+ salvage.

DOI 10.64898/2026.07.23.740149

NeuroscienceCell Death and DiseasePeer-reviewedJul 31, 2021

Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB

Tsui-Wen Chou, Nydia P. Chang, Medha Krishnagiri…·Brian P. Daniels

This study shows that α-synuclein fibrils activate midbrain astrocytes through RIP kinase and NF-κB signaling, leading to neurotoxicity and inflammation in Parkinson's disease.

90 citationstop 2%

humanstatistical model