Author

Diego Alzate

Rutgers, The State University of New Jersey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Brian P. DanielsiD· 2 shared Colm AtkinsiD· 2 shared Marissa LindmaniD· 2 shared Alexander W. KusnecoviD· 1 shared Evan M. DaPranoiD· 1 shared Irving EsteveziD· 1 shared Juan P. AngeliD· 1 shared Marialaina Nissenbaum· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Brian P. DanielsORCID

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2 papers

Recent·Most cited

SIRT1 remodels astrocyte metabolism and promotes viral replication during neurotropic orthoflavivirus infection

Juan P. Angel, Diego Alzate, Marissa Lindman, Colm Atkins, Brian P. Daniels

This study shows SIRT1 promotes viral replication in astrocytes during orthoflavivirus infection by altering metabolism and NAD+ salvage.

bioRxiv · Jul 24, 2026 · PreprintImmunology

Neuronal DAMPs exacerbate neurodegeneration via astrocytic RIPK3 signaling

Nydia P. Chang, Evan M. DaPrano, Marissa Lindman, Irving Estevez, Tsui-Wen Chou, Wesley R. Evans, Marialaina Nissenbaum, Micheal McCourt, Diego Alzate, Colm Atkins, Alexander W. Kusnecov, Rafiq Huda, Brian P. Daniels

This study shows that neuronal DAMPs activate astrocytic RIPK3 signaling, leading to neuroinflammation and dopaminergic cell death in Parkinson's disease.

JCI Insight · May 7, 2024Peer-reviewedNeuroscience