Author

Reafa A. Hossain

Virginia Commonwealth UniversityORCID 0000-0002-3113-8921Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aanchal Dubey· 1 shared Alexander L. SchmidtiD· 1 shared Apurva Tadimari PrabhakariD· 1 shared Aya H. Youssef· 1 shared Christopher BerndseniD· 1 shared Claire D. JamesiD· 1 shared D. Thor JohnsoniD· 1 shared Da ChengiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMolecular Biology

Aanchal Dubey

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3 papers

Recent·Most cited

ImmunologyJournal of VirologyPeer-reviewedApr 3, 2026

Systemic translocation of Staphylococcus aureus promotes autoimmunity: implications in autoantibody-mediated poor immune reconstitution from antiretroviral therapy in HIV

Da Cheng, Zhenwu Luo, Wangbin Ning…·Wei Jiang

This study shows that Staphylococcus aureus translocation promotes anti-CD4 autoantibodies in HIV patients on ART, impairing CD4+ T cell recovery.

DOI 10.1128/jvi.01965-25

humanproteomics

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Molecular BiologybioRxivPreprintJan 15, 2024

A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels

Apurva Tadimari Prabhakar, Claire D. James, Aya H. Youssef…·Iain M. Morgan

This paper identifies a mitotic E2-TopBP1 complex that inactivates SIRT1, promoting E2 acetylation and stability through p300, which protects against ubiquitination and proteasomal degradation.

3 citations

humanproteomics

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Molecular BiologybioRxivPreprintAug 22, 2017

Modeling of Epigenetic Modification-Induced Changes in CRX-dependent Genes cis-Regulatory Elements

Reafa A. Hossain, Nicholas R. Dunham, Megan E. Harris…·Christopher Berndsen

The paper models how DNA methylation affects CRX binding to regulatory elements of RHO and PDE6B genes in human ocular tissues, showing inverse correlations and structural changes in DNA grooves.

DOI 10.1101/179523

humanDNA methylation

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