Author

Daniel J. Bruzzese

Yale UniversityORCID 0000-0002-3115-6599Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

Brian L. WeissiD· 2 shared Erick O. AwuocheiD· 2 shared Gretchen M. Smallenberger· 2 shared Serap AksoyiD· 2 shared Adly M. M. Abd‐AllaiD· 1 shared Alessandra Silva OrfanoiD· 1 shared Anna Rodolfa MalacridaiD· 1 shared Aurel HolzschuhiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersMicrobiology

Brian L. WeissORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Endosymbiont hijacking of acylcarnitines regulates insect vector fecundity by suppressing the viability of stored sperm

Brian L. Weiss, Fabian Gstöttenmayer, Erick O. Awuoche, Gretchen M. Smallenberger, Geoffrey Michael Attardo, Francesca Scolari, Robert Tobias Koch, Daniel J. Bruzzese, Richard Echodu, Robert Opiro, Anna Rodolfa Malacrida, Adly M. M. Abd‐Alla, Serap Aksoy

This study shows that Spiroplasma endosymbionts in tsetse flies compete with sperm for acylcarnitines, reducing sperm motility and fly fecundity.

PLoS Genetics · Dec 10, 2025Peer-reviewedMicrobiology

Spiroplasma endosymbiont reduction of host lipid synthesis and Stomoxyn-like peptide contribute to trypanosome resistance in the tsetse fly Glossina fuscipes

Erick O. Awuoche, Gretchen M. Smallenberger, Daniel J. Bruzzese, Alessandra Silva Orfano, Brian L. Weiss, Serap Aksoy

This study identifies Spiroplasma-induced lipid reduction and a Stomoxyn-like peptide as mechanisms contributing to trypanosome resistance in tsetse flies.

PLoS Pathogens · Jan 31, 2025Peer-reviewedMolecular Biology

Rapid evolution of Wolbachia in cherry fruit flies

Daniel J. Bruzzese, Hannes Schuler, Wee L. Yee, Aurel Holzschuh, Jeffrey L. Feder

This study investigates rapid genome evolution of Wolbachia in cherry fruit flies, revealing structural and gene content changes over ecological timeframes.

bioRxiv · Jan 13, 2025 · PreprintEvolutionary Biology