Author

Brian L. Weiss

Yale UniversityORCID 0000-0003-1576-3556Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Immunology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Serap AksoyiD· 4 shared Erick O. AwuocheiD· 3 shared Adly M. M. Abd‐AllaiD· 2 shared Alessandra Silva OrfanoiD· 2 shared Anna Rodolfa MalacridaiD· 2 shared Aurélien VigneroniD· 2 shared Daniel J. BruzzeseiD· 2 shared Francesca ScolariiD· 2 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

Serap AksoyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologyPLoS PathogensPeer-reviewedMay 4, 2026

PGRP-LA regulates peritrophic matrix synthesis and influences trypanosome infection outcomes in tsetse flies

Aurélien Vigneron, Brian L. Weiss, Yuebiao Feng…·Serap Aksoy

This study identifies PGRP-LA as a regulator of peritrophic matrix integrity in tsetse flies, influencing trypanosome infection outcomes by modulating gut barrier function rather than canonical immune signaling.

DOI 10.1371/journal.ppat.1013520

bulk RNA-seqexperimental assay

𝕏 PostBluesky

MicrobiologyPLoS GeneticsPeer-reviewedDec 10, 2025

Endosymbiont hijacking of acylcarnitines regulates insect vector fecundity by suppressing the viability of stored sperm

Brian L. Weiss, Fabian Gstöttenmayer, Erick O. Awuoche…·Serap Aksoy

This study shows that Spiroplasma endosymbionts in tsetse flies compete with sperm for acylcarnitines, reducing sperm motility and fly fecundity.

2 citations

proteomicsmetabolomics

𝕏 PostBluesky

Molecular BiologyPLoS PathogensPeer-reviewedJan 31, 2025

Spiroplasma endosymbiont reduction of host lipid synthesis and Stomoxyn-like peptide contribute to trypanosome resistance in the tsetse fly Glossina fuscipes

Erick O. Awuoche, Gretchen M. Smallenberger, Daniel J. Bruzzese…·Serap Aksoy

This study identifies Spiroplasma-induced lipid reduction and a Stomoxyn-like peptide as mechanisms contributing to trypanosome resistance in tsetse flies.

7 citationstop 5%

bulk RNA-seqstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintJan 27, 2019

The Glossina Genome Cluster: Comparative Genomic Analysis of the Vectors of African Trypanosomes

Geoffrey Michael Attardo, Adly M. M. Abd‐Alla, Álvaro Acosta-Serrano…·Serap Aksoy

The paper presents a comparative genomic analysis of six Glossina species, identifying genetic features related to their unique biology and vectorial capacity.

6 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky