Sanamjeet Virdi

This study identifies small-molecule inhibitors of BK polyomavirus infection through phenotypic screening, revealing compounds with distinct antiviral mechanisms and cellular effects.

This study shows that deficiency of cytotoxic CD8 T cells in early life leads to limited protection against cytomegalovirus infection.

This study shows that defective HIV-1 proviruses can reprogram CD4+ T cells by altering BACH2 and STAT5B gene expression, leading to immune evasion and persistence in ART-treated individuals.

This paper demonstrates that iPSC-derived skin organoids support MCPyV infection, persistence, and tumor development, providing a model to study viral interactions with the immune system and treatment strategies.

This study identifies FAM111B as a host restriction factor that suppresses mouse cytomegalovirus replication in human and rhesus macaque cells through E2F3-dependent activation.