Author

Silvia Albertini

University Medical Center Hamburg-EppendorfORCID 0000-0002-8540-5378Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:spatial transcriptomics· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam T. GrundhoffiD· 2 shared Carola Schneider· 2 shared Emanuel WyleriD· 2 shared Manja Czech‐SioliiD· 2 shared Markus LandthaleriD· 2 shared Nicole FischeriD· 2 shared Susanne KrasemanniD· 2 shared Annalena Winterfeldt· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Adam T. GrundhoffORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Spatially organized inflammatory myeloid-CD8+ T cell aggregates linked to Merkel-cell Polyomavirus driven Reorganization of the Tumor Microenvironment

Maximilian Haist, Magdalena Matusiak, Yuqi Tan, S. Zimmer, Henner M. Stege, Tim Noah Kempchen, Silke Mitschke, Pauline Chu, Beate Weidenthaler‐Barth, Graham L. Barlow, Friederike Rogall, Antonio Delgado‐González, Marc‐Andrea Baertsch, Silvia Albertini, Marisa Gariglio, , Garry P. Nolan

The paper identifies spatial immune patterns in Merkel cell carcinoma linked to viral status and patient outcomes.

bioRxiv · Jun 6, 2025 · PreprintImmunology

Merkel cell polyomavirus infection and persistence modelled in skin organoids

Silvia Albertini, Manja Czech‐Sioli, Thomas Günther, Sanamjeet Virdi, Patrick Blümke, Lisann Röpke, Veronika Brinschwitz, Maura Dandri, Lena Allweiss, Rudolf Reimer, Carola Schneider, Arne Hansen, Susanne Krasemann, Emanuel Wyler, Markus Landthaler, , Nicole Fischer

This paper demonstrates that iPSC-derived skin organoids support MCPyV infection, persistence, and tumor development, providing a model to study viral interactions with the immune system and treatment strategies.

bioRxiv · Feb 11, 2025 · PreprintMolecular Biology

Complex Human hear bearing Skin Organoids reveal Cell Type Specific Susceptibility and Innate Immune Responses to Herpes Simplex Virus 1

Emanuel Wyler, Silvia Albertini, Caroline C. Friedel, Artür Manukyan, Annalena Winterfeldt, Nina Bracker, Jiabin Huang, Susanne Krasemann, Izabela Plumbom, Janine Altmüller, Thomas Conrad, Rudolph Reimer, Carola Schneider, Helena Radbruch, Wali Hafezi, , Manja Czech‐Sioli

This study uses human hair-bearing skin organoids to investigate HSV-1 infection and host responses, revealing cell-type-specific susceptibility and spatially organized immune reactions.

bioRxiv · Feb 10, 2025 · PreprintMicrobiology