Life without heterotrimeric kinesins: trypanosomatids use a combination of homodimeric kinesin-2 motors to drive intraflagellar transport
Aline Araujo Alves, Augustine Cleetus, Cécile Fort, Kristína Záhonová, Daniel Abbühl, Christine Girard-Blanc, Thierry Blisnick, Serge Bonnefoy, Nadège Cayet, Ziyin Wang, Jack Daniel Sunter, Vyacheslav Yurchenko, Richard John Wheeler, Zeynep Ökten, Philippe Bastin
This study shows trypanosomatids use homodimeric kinesin-2 motors KIN2A and KIN2B for intraflagellar transport, with KIN2B being essential and KIN2A having a more limited role.
bioRxiv · Aug 10, 2026 · PreprintCell Biology