BioengineeringComputational and Structural Biotechnology JournalPeer-reviewed
Identification of Cellular Signatures Associated with Chinese Hamster Ovary (CHO) Cell Adaptation for Secretion of Antibodies
Ying Bai, Ivan Domenech Mercadé, Ramy Elgendy…·Rajesh K. Mistry
This study identifies cellular adaptations in CHO cells linked to antibody production, finding that transgene copy number and mRNA expression levels are key factors in productivity.
6 citations