Author

Elizabeth A. Macdonald

Ottawa Hospital Research InstituteORCID 0000-0002-3154-9632Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alyssa Murray· 1 shared Anne‐Marie Mes‐MassoniD· 1 shared Barbara C. VanderhydeniD· 1 shared Curtis W. McCloskeyiD· 1 shared David A. LandryiD· 1 shared Dominique TrudeliD· 1 shared Edward YakubovichiD· 1 shared Euihye JungiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alyssa Murray

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1 paper

Recent·Most cited

BRCA mutation alters the stromal landscape in normal ovaries

Het T. Vaishnav, Alyssa Murray, Olivia R. Piccolo, Curtis W. McCloskey, Edward Yakubovich, Elizabeth A. Macdonald, Maryam Echaibi, Manon de Ladurantaye, Euihye Jung, Thomas J. Fazio, Dominique Trudel, Anne‐Marie Mes‐Masson, Ronny Drapkin, David A. Landry, Barbara C. Vanderhyden

This study shows BRCA mutations alter ovarian stromal structure by promoting fibroblast senescence and myofibroblastic transformation, creating a metastatic niche for early ovarian cancer.

bioRxiv · Oct 1, 2025 · PreprintMolecular Biology