Author

Edward Yakubovich

University of OttawaORCID 0000-0002-2109-1111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Abrar Ul Haq KhaniD· 1 shared Alyssa Murray· 1 shared Anne‐Marie Mes‐MassoniD· 1 shared Ayad AliiD· 1 shared Barbara C. VanderhydeniD· 1 shared Christiano Tanese de SouzaiD· 1 shared Colin O’DwyeriD· 1 shared Curtis W. McCloskeyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Abrar Ul Haq KhanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BRCA mutation alters the stromal landscape in normal ovaries

Het T. Vaishnav, Alyssa Murray, Olivia R. Piccolo, Curtis W. McCloskey, Edward Yakubovich, Elizabeth A. Macdonald, Maryam Echaibi, Manon de Ladurantaye, Euihye Jung, Thomas J. Fazio, Dominique Trudel, Anne‐Marie Mes‐Masson, Ronny Drapkin, David A. Landry, Barbara C. Vanderhyden

This study shows BRCA mutations alter ovarian stromal structure by promoting fibroblast senescence and myofibroblastic transformation, creating a metastatic niche for early ovarian cancer.

bioRxiv · Oct 1, 2025 · PreprintMolecular Biology

LAG3 marks activated but hyporesponsive NK cells.

Valeria Vasilyeva, Olivia Makinson, Cynthia S. Y. Chan, M. Park, Colin O’Dwyer, Ayad Ali, Abrar Ul Haq Khan, Christiano Tanese de Souza, Mohamed S. Hasim, Sara Asif, Reem Kurdieh, John Abou‐Hamad, Edward Yakubovich, Jonathan J. Hodgins, Paul Al Haddad, , Marie Marotel

This study identifies LAG3 as a marker of dysfunctional NK cells that are activated but hyporesponsive in various inflammatory conditions.

European Journal of Immunology · Jul 1, 2025Peer-reviewedImmunology