Author

Vivien R. Sutton

Peter MacCallum Cancer CentreORCID 0000-0002-3156-7355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Akash Srivaths· 1 shared Aleen Al HalawaniiD· 1 shared Andreas BehreniD· 1 shared Anne Huber· 1 shared Bhupinder PaliD· 1 shared Chloe Gerak· 1 shared Conor J. KearneyiD· 1 shared Daire Gannon· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Akash Srivaths

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMay 9, 2025

A TAK1Cytokine Toxicity Checkpoint Controls Anti-Cancer Immunity

Tirta Mario Djajawi, Anne Huber, S. Rivera…·Conor J. Kearney

This study identifies TAK1 as a cancer-intrinsic checkpoint that limits CD8+ T cell-mediated anti-cancer immunity by suppressing TNF and IFNγ-induced apoptosis, and shows that targeting TAK1 enhances anti-tumor responses.

DOI 10.1101/2025.05.09.652721

mousegenetic perturbation / CRISPR

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