Author

Gülen Güney-Esken

Koç UniversityORCID 0000-0002-3158-1587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Füsun CaniD· 2 shared Alişan KayaböleniD· 1 shared Berna ÖzeriD· 1 shared Canan BayraktariD· 1 shared Cem AlbayrakiD· 1 shared Doğancan ÖzturaniD· 1 shared Ehsan SaraylooiD· 1 shared Elif NurtopiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Füsun CanORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 2, 2025

PM2.5 Exposure Facilitates SARS-CoV-2 Infection through ACE2/TMPRSS2 Regulation and Suppression of Anti-Viral Response

Hadi Rajabi, Özgecan Kayalar, Gülen Güney-Esken…·Hasan Bayram

This study shows PM2.5 exposure increases ACE2 and TMPRSS2 expression and reduces antiviral responses, facilitating SARS-CoV-2 infection in airway epithelial cells.

DOI 10.1101/2025.10.02.679237

humanbulk RNA-seq

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Molecular BiologyAdvanced SciencePeer-reviewedJul 27, 2022

Protein scaffold-based multimerization of soluble ACE2 efficiently blocks SARS-CoV-2 infection in vitro and in vivo

Alişan Kayabölen, Uğur Akcan, Doğancan Özturan…·Tugba Bagci Onder

The paper develops multimeric sACE2 decoys using SunTag or MoonTag systems, showing >100-fold increased SARS-CoV-2 neutralization compared to monomeric sACE2.

16 citations

humanmouse

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