Swati R. Manjari

The paper analyzes how medically important antimicrobials bind to the 30S ribosomal subunit of Borrelia burgdorferi using structural analogy and computational methods to predict binding free energy.

This study reveals how mycobacterial HflX mediates ribosome splitting and antibiotic resistance through rRNA disordering and anti-association mechanisms.

This study identifies a novel actinobacteria-specific ribosome tunnel occlusion factor in Mtb that blocks nascent polypeptide exit and interferes with drug binding during ribosome hibernation.

This study identifies genetic and metabolic adaptations in pan-drug resistant Candida auris strains that enable resistance without fitness costs.

This study identifies how mycobacterial Rsh detects deacylated tRNA in translating ribosomes through structural and functional analysis, revealing its constitutive surveillance mechanism.