Author

Laurine Buscara

Genethon (France)ORCID 0000-0002-3175-4302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alexia Castiglione· 1 shared Antonia RattiiD· 1 shared Delphine BohliD· 1 shared Genries-Ferrand Sandrine· 1 shared Georges Arielle PêcheiD· 1 shared Jennifer HuaiD· 1 shared Julia P. LemosiD· 1 shared Mara RigamontiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alexia Castiglione

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1 paper

Recent·Most cited

Pre-clinical evaluation of a gene therapy candidate for SOD1-ALS shows improved survival and signs of inflammation in the CNS of treated mice.

Sonia Pezet, Jennifer Hua, Thibaut Marais, Marine Delamare, Sahar Elouej, Julia P. Lemos, Alexia Castiglione, Stéphanie Astord, Mathilde Cohen-Tannoudji, Georges Arielle Pêche, Mara Rigamonti, Nathalie Danièle, Genries-Ferrand Sandrine, Laurine Buscara, Antonia Ratti, , Maria Grazia Biferi

This study evaluates a gene therapy for SOD1-ALS, showing improved survival and CNS inflammation in treated mice with dose-dependent hSOD1 reduction.

bioRxiv · Oct 16, 2025 · PreprintPharmacology & Toxicology