Author

Thibaut Marais

InsermORCID 0000-0002-1968-193XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Piera SmeriglioiD· 2 shared Sonia PezetiD· 2 shared Alexia Castiglione· 1 shared Aly BourguibaiD· 1 shared Antonia RattiiD· 1 shared Antonio MusaròiD· 1 shared Aurélie Fail· 1 shared Bruno CadotiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

Piera SmeriglioORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GDF5 as a Multimodal Protector of the Motor Unit in Amyotrophic Lateral Sclerosis

Aly Bourguiba, Sonia Pezet, Massiré Traoré, Christel Gentil, Thibaut Marais, Aurélie Fail, Maxime Gelin, Julien Messéant, Pierre Meunier, Sofia Benkhelifa‐Ziyyat, Zoheir Guesmia, Bruno Cadot, Antonio Musarò, Gabriella Dobrowolny, Julianne Perronnet, , France Piétri‐Rouxel

This study identifies GDF5 as a protective factor in ALS by restoring SMAD signaling and preserving motor unit integrity through gene delivery in a mouse model.

bioRxiv · Jul 3, 2026 · PreprintPhysiology

Pre-clinical evaluation of a gene therapy candidate for SOD1-ALS shows improved survival and signs of inflammation in the CNS of treated mice.

Sonia Pezet, Jennifer Hua, Thibaut Marais, Marine Delamare, Sahar Elouej, Julia P. Lemos, Alexia Castiglione, Stéphanie Astord, Mathilde Cohen-Tannoudji, Georges Arielle Pêche, Mara Rigamonti, Nathalie Danièle, Genries-Ferrand Sandrine, Laurine Buscara, Antonia Ratti, , Maria Grazia Biferi

This study evaluates a gene therapy for SOD1-ALS, showing improved survival and CNS inflammation in treated mice with dose-dependent hSOD1 reduction.

bioRxiv · Oct 16, 2025 · PreprintPharmacology & Toxicology