Author

Jennifer Hua

Centre National de la Recherche ScientifiqueORCID 0000-0003-2014-918XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexia Castiglione· 1 shared Amazigh MokhtariiD· 1 shared Andrée Delahaye‐DurieziD· 1 shared Antonia RattiiD· 1 shared Ariane Heydari OlyaiD· 1 shared Bénédicte ManouryiD· 1 shared Bobbi FleissiD· 1 shared Boris MatrotiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alexia Castiglione

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 16, 2025

Pre-clinical evaluation of a gene therapy candidate for SOD1-ALS shows improved survival and signs of inflammation in the CNS of treated mice.

Sonia Pezet, Jennifer Hua, Thibaut Marais…·Maria Grazia Biferi

This study evaluates a gene therapy for SOD1-ALS, showing improved survival and CNS inflammation in treated mice with dose-dependent hSOD1 reduction.

DOI 10.1101/2025.10.16.682744

mouseexperimental assay

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NeuroscienceBrain Behavior and ImmunityPeer-reviewedOct 21, 2024

C-section and systemic inflammation synergize to disrupt the neonatal gut microbiota and brain development in a model of prematurity

Cécile Morin, Flora Faure, Julie Mollet…·Cindy Bokobza

This study shows that C-sections combined with systemic inflammation worsen brain and gut issues in a preterm mouse model, increasing neurodevelopmental risks.

14 citationstop 2%

mouseexperimental assay

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NeurosciencebioRxivPreprintMay 12, 2022

Microglial P2X4 receptors promote ApoE degradation and cognitive deficits in Alzheimer disease

Jennifer Hua, Elvira Garcia De Paco, Nathalie Linck…·Lauriane Ulmann

This study shows that microglial P2X4 receptors promote ApoE degradation and cognitive deficits in Alzheimer's disease by enhancing lysosomal activity and reducing Aβ clearance.

DOI 10.1101/2022.05.12.491601

mouseproteomics

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