Author

Kaz M. Knight

Colorado State UniversityORCID 0000-0002-3184-3620Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Frédéric J. HoerndliiD· 3 shared Rachel L. DoseriD· 3 shared Ennis W. DeihliD· 2 shared Zephyr LenningeriD· 2 shared Amy C. GoldsteiniD· 1 shared Aneal KhaniD· 1 shared April N. LehmaniD· 1 shared Arnaud Vincent VanlanderiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersNeuroscience

Frédéric J. HoerndliORCID

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Author profile →

4 papers

Recent·Most cited

The clinical utility of functional testing in fibroblasts to diagnose primary mitochondrial disease

Johan L.K. Van Hove, Marisa W. Friederich, Roxanne A. Van Hove, Jessica C. Lee, Kaz M. Knight, Tonia E. Donovan, Lori Silveira, Rebecca D. Ganetzky, Michio Hirano, José E. Abdenur, Merlin G. Butler, David M Cassiman, Bruce H. Cohen, Sarah H. Elsea, Gregory M. Enns, , Jennifer H. Yang

Four mitochondrial functional tests in fibroblasts show good sensitivity and excellent specificity for diagnosing primary mitochondrial disease.

medRxiv · Jun 15, 2026 · PreprintGenetic & Genomic Medicine

Activity-Dependent Postsynaptic Mitochondrial ROS Signaling Drives Avoidance Plasticity in C. elegans

Kaz M. Knight, Zephyr Lenninger, Ennis W. Deihl, Rachel L. Doser, Frédéric J. Hoerndli

This paper shows that activity-dependent mitochondrial ROS signaling in C. elegans drives avoidance plasticity by enhancing synaptic strength and circuit function.

bioRxiv · Jun 12, 2026 · PreprintNeuroscience

Activity-dependent Mitochondrial ROS Signaling Regulates Recruitment of Glutamate Receptors to Synapses

Rachel L. Doser, Kaz M. Knight, Ennis W. Deihl, Frédéric J. Hoerndli

The paper demonstrates that mitochondrial ROS signaling in C. elegans regulates synaptic recruitment of glutamate receptors by modulating calcium uptake and reactive oxygen species production.

eLife · Mar 14, 2024Peer-reviewedNeuroscience

A Dual Role for LAR-RPTP in Regulating Long-distance Transport and Synaptic Retention of AMPARs, Essential for Long Term Associative Memory

D.M. Pierce, Zephyr Lenninger, Rachel L. Doser, Kaz M. Knight, Attila Steták, Frédéric J. Hoerndli

This study shows that PTP-3A regulates AMPAR transport and synaptic retention in C. elegans, essential for long-term associative memory.

bioRxiv · Aug 11, 2022 · PreprintNeuroscience