FoxO factors preserve airway epithelial homeostasis by coordinating adaptive stress responses
Karin Uliczka, Judith Bossen, Ulrich M. Zissler, Christine Fink, Xiao Niu, Mario Pieper, Ruben D. Prange, Christina Vock, Christina Wagner, Mirjam Knop, Ahmed Abdelsadik, Sören Franzenburg, Iris Bruchhaus, Michael Wegmann, Carsten B. Schmidt-Weber, , Thomas Roeder
The paper shows FoxO factors in Drosophila, mouse, and human airway epithelial cells respond to stressors by nuclear translocation, with FoxO-dependent stress pathways altered in asthma across species.
bioRxiv · Jan 31, 2024 · PreprintPhysiology