Author

Jessica Eden

University of CambridgeORCID 0000-0002-3204-5583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Organism:rat· 1

Frequent Co-Authors

David C. GershlickiD· 2 shared Amber S. Shun-ShioniD· 1 shared Bart NieuwenhuisiD· 1 shared Conceição PereiraiD· 1 shared Daniel J. FazakerleyiD· 1 shared Danièle StalderiD· 1 shared David J. OweniD· 1 shared Edson Mendes de OliveiraiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

David C. GershlickORCID

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2 papers

Recent·Most cited

Cell BiologyThe EMBO JournalPeer-reviewedAug 26, 2025

RABGAP1 acts as a sensor to facilitate sorting and processing of amyloid precursor protein

Jessica Eden, Jonathan G. G. Kaufman, Conceição Pereira…·David C. Gershlick

This study identifies RABGAP1 as a sensor that modulates APP trafficking and processing by regulating RAB activity on endosomal subdomains, with implications for Alzheimer's disease.

3 citations

humanrat

Cell BiologyJournal of Biological ChemistryPeer-reviewedJul 14, 2024

A quantitative pipeline to assess secretion of human leptin coding variants reveals mechanisms underlying leptin deficiencies

Harry J. M. Baird, Amber S. Shun-Shion, Edson Mendes de Oliveira…·Daniel J. Fazakerley

This study develops a medium-throughput assay to assess leptin secretion and identifies mutations causing proteasomal degradation or reduced secretion.

DOI 10.1016/j.jbc.2024.107562

humanproteomics