Cancer BiologyCancer Immunology ResearchPeer-reviewed
The CCL17-CCR4 axis is critical for mutant STAT6-mediated microenvironmental remodelling and therapeutic resistance in Relapsed/Refractory Diffuse Large B Cell Lymphoma
Madelyn Jean Abraham, Cynthia Guilbert, Natascha Gagnon…·Koren Kathleen Mann
This study identifies the CCL17-CCR4 axis as a driver of therapeutic resistance in STAT6D419 mutant rrDLBCL by promoting T cell infiltration and microenvironmental changes.
DOI 10.1158/2326-6066.cir-25-0583