Arianna O. Osgood

An efficient opal-suppressor tryptophanyl pair creates new routes for simultaneously incorporating up to three distinct noncanonical amino acids into proteins in mammalian cells

This paper introduces an efficient method to incorporate up to three distinct noncanonical amino acids into proteins in mammalian cells using a combination of orthogonal aaRS/tRNA pairs.

A facile platform to engineer E. coli tyrosyl-tRNA synthetase adds new chemistries to the eukaryotic genetic code, including a phosphotyrosine mimic

This paper describes an engineered E. coli tyrosyl-tRNA synthetase system that enables the incorporation of new noncanonical amino acids into eukaryotic cells.