Delilah Jewel

This paper describes a chemical strategy to create AAV-protein conjugates for targeted gene delivery, showing efficient and selective transduction of HER2+ cancer cells with minimal off-target effects.

This paper improves the efficiency of noncanonical amino acid incorporation in mammalian cells by evolving tRNAEcLeu through directed evolution in mammalian cells.

This paper introduces an efficient method to incorporate up to three distinct noncanonical amino acids into proteins in mammalian cells using a combination of orthogonal aaRS/tRNA pairs.

This paper develops VADER, a virus-assisted directed evolution method for improving suppressor tRNAs in mammalian cells, resulting in more active and orthogonal tRNA mutants.