Taro Tsujimura

Personalized reference genome-based pipeline reveals comprehensive haplotype-resolved views of cancer genomes

PRCGAP provides a haplotype-resolved analysis of cancer genomes, detecting variants missed by standard references and revealing new insights into structural variants and fusion events in leukemia.

Towards On-Site Paleogenomics: Application and Perspective of Nanopore Sequencing with Ancient DNA

This study applies nanopore sequencing to ancient DNA from the Early Jomon period, demonstrating its ability to generate genome-wide data and enable rapid, on-site paleogenomic analysis.

Rare k-mers reveal centromere haplogroups underlying human diversity and cancer translocations

This paper uses rare k-mers to identify centromere haplogroups in human populations and cancer translocations, revealing structural diversity and translocation mechanisms.

Reconstituting human somitogenesis in vitro

This paper introduces a 3D in vitro model of human somitogenesis using pluripotent stem cells, showing accurate segmentation dynamics and disease relevance.

Controlling gene activation by enhancers through a drug-inducible topological insulator

The paper develops a drug-inducible system to control gene activation by enhancers using a synthetic topological insulator and demonstrates its application in regulating MYC in human pluripotent stem cells.