Andrea L. Smidler

This study develops split suppression gene drives in Aedes aegypti, showing that inheritance efficiency and reproductive fitness costs must be balanced for effective population suppression.

The paper develops and characterizes gene drive docking lines in Anopheles gambiae using RMCE and HACK techniques, identifies challenges for robust gene drive development.

This paper evaluates the cost-effectiveness of precision-guided sterile insect technique (pgSIT) for malaria control in The Gambia, finding it to be a cost-effective and economically beneficial approach.

This paper develops a CRISPR-based genetic sterilization system for Anopheles gambiae males, achieving high infertility rates and population suppression in competition cages.