Author

Jesse R. Pascual

University of California, IrvineORCID 0000-0002-3307-0887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Elizabeth HeadiD· 1 shared Haipeng XueiD· 1 shared Haiwei ZhangiD· 1 shared Mengmeng JiniD· 1 shared Peng JiangiD· 1 shared Rachael KimiD· 1 shared Rui Dang· 1 shared Steven M. FinkbeineriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Elizabeth HeadORCID

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Author profile →

1 paper

Recent·Most cited

A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimers Disease

Mengmeng Jin, Ziyuan Ma, Rui Dang, Haiwei Zhang, Rachael Kim, Haipeng Xue, Jesse R. Pascual, Steven M. Finkbeiner, Elizabeth Head, Ying Min Liu, Peng Jiang

This paper introduces a trisomy 21-linked CSF2RB mutation in microglia that reduces neuroinflammation and enhances phagocytic functions, offering potential for AD therapy.

bioRxiv · Mar 12, 2024 · PreprintNeuroscience