Sven Findeiß

Telomerase RNA gene duplications drive telomeric repeatdiversity and evolution in Andrena bees

The paper identifies multiple TR gene copies in Andrena bees that generate diverse telomeric repeats, showing TR gene duplication drives telomere sequence diversity in insects.

Tailored machine learning models for functional RNA detection in genome-wide screens

The paper introduces a software framework for training and evaluating machine learning models to detect functional RNA in genome-wide screens, demonstrating its use in Drosophila melanogaster.

Beyond Plug and Pray: Context Sensitivity and in silico Design of Artificial Neomycin Riboswitches

The paper designs synthetic neomycin-responsive riboswitches and shows that their function depends on sequence context, introducing in silico methods to improve design.

Assessing the Quality of Cotranscriptional Folding Simulations

The paper introduces BarMap-QA, a pipeline for assessing the quality of cotranscriptional folding simulations of RNA elements.

In silico design of ligand triggered RNA switches

This paper describes an in silico workflow for designing RNA switches that change structure in response to ligands, using a theophylline aptamer as an example.

Quantitative characterization of translational riboregulators using an in vitro transcription-translation system

This paper quantitatively characterizes in silico designed riboregulators using a cell-free TX-TL system to measure their performance and dissociation constants.