Author

Timothy Connelley

Roslin InstituteORCID 0000-0002-3313-5441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:chicken / avian· 1 Research Focus:database / resource· 1 Research Focus:genome assembly· 1 Approach:graph neural network· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Andrea TalentiiD· 3 shared David WraggiD· 3 shared James G. D. PrendergastiD· 3 shared Jessica PowelliD· 3 shared Philip G. ToyeiD· 3 shared Andressa FischiD· 2 shared Beatriz Rossetti FerreiraiD· 2 shared Chukwunonso EzeasoriD· 2 shared

Activity by Year

2022-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Andrea TalentiORCID

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Author profile →

4 papers

Recent·Most cited

Analysis of genetic variation in the bovine Mannose Receptor gene (MRC1), its influence on receptor expression, and a potential association with resistance to bovine tuberculosis

Angela L Holder, Jeannine Kolakowski, Eike Usher, Thomas Tzelos, Timothy Connelley, Muhammad Zubair Shabbir, Amanda J. Gibson, Heather Harris, Bernardo Villarreal‐Ramos, Dirk Werling

The paper identifies genetic variants in the bovine MRC1 gene, analyzes their impact on receptor expression, and explores their potential role in bovine tuberculosis resistance.

bioRxiv · Jul 3, 2026 · PreprintImmunology

Optical mapping compendium of structural variants across global cattle breeds

Andrea Talenti, Jessica Powell, David Wragg, Maurine C. Chepkwony, Andressa Fisch, Beatriz Rossetti Ferreira, Maria Eugênia Zerlotti Mercadante, Isabel Kinney Ferreira de Miranda Santos, Chukwunonso Ezeasor, Emmanuel Obishakin, Dennis Muhanguzi, Wilson Amanyire, Isaac Silwamba, John Muma, Geoffrey Mainda, , James G. D. Prendergast

This study uses optical mapping to identify structural variants in cattle breeds, providing a database for further genetic and evolutionary studies.

Scientific Data · Oct 13, 2022Peer-reviewedGenomics

A locus conferring tolerance to Theileria infection in African cattle

David Wragg, Elizabeth A. J. Cook, Perle Latré de Laté, Tatjana Sitt, Johanneke Dinie Hemmink, Maurine C. Chepkwony, Regina Njeru, Elizabeth Jane Poole, Jessica Powell, Edith A. Paxton, Rebecca Callaby, Andrea Talenti, Antoinette Aluoch Miyunga, Gideon Ndambuki, Stephen Mwaura, , James G. D. Prendergast

The paper identifies a genetic locus associated with tolerance to Theileria parva infection in cattle, showing a strong heritability and replication across cohorts.

PLoS Genetics · Apr 21, 2022Peer-reviewedGenetics

A cattle graph genome incorporating global breed diversity

Andrea Talenti, Jessica Powell, Johanneke Dinie Hemmink, Elizabeth A. J. Cook, David Wragg, Siddharth Jayaraman, Edith A. Paxton, Chukwunonso Ezeasor, Emmanuel Obishakin, Ebere Roseann Agusi, Abdulfatai Tijjani, Wilson Amanyire, Dennis Muhanguzi, K. Marshall, Andressa Fisch, , James G. D. Prendergast

The paper creates a graph genome incorporating global cattle diversity, showing it includes more sequence and improves mapping and variant calling.

Nature Communications · Feb 17, 2022Peer-reviewedGenomics