Author

Cong Lyu

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Assay:proteomics· 2

Frequent Co-Authors

Hailin WangiD· 3 shared Hongwei ZhouiD· 2 shared Jianlong WangiD· 2 shared Vikas MalikiD· 2 shared Xin HuangiD· 2 shared André MateusiD· 1 shared Andrea MatteviiD· 1 shared Ángel RomániD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersDevelopmental Biology

Hailin WangORCID

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3 papers

Recent·Most cited

The catalytic-independent function of LSD1 modulates the epigenetic landscape of mouse embryonic stem cells

Sandhya Malla, Kanchan Kumari, Carlos Martinez‐Gamero, Carlos Antonio García-Prieto, Stephanie Stransky, Jonatan Caroli, Damiana Álvarez‐Errico, Paulina Avovome Saiki, Weiyi Lai, Cong Lyu, Jonathan D. Gilthorpe, Hailin Wang, Simone Sidoli, Andrea Mattevi, André Mateus, , Francesca Aguiló

This study shows that LSD1's non-catalytic function regulates DNA methylation in mouse ESCs by controlling UHRF1 and DNMT1 stability through USP7 interaction.

bioRxiv · Jun 29, 2023 · PreprintMolecular Biology

ZFP281 coordinates DNMT3 and TET1 for transcriptional and epigenetic control in pluripotent state transitions

Xin Huang, Sophie Balmer, Cong Lyu, Yunlong Xiang, Vikas Malik, Hailin Wang, Yu Zhang, Wei Xie, Anna‐Katerina Hadjantonakis, Hongwei Zhou, Jianlong Wang

This study identifies ZFP281 as a coordinator of DNMT3A/3B and TET1 to regulate DNA methylation and gene expression during pluripotent stem cell state transitions.

bioRxiv · Mar 24, 2023 · PreprintDevelopmental Biology

A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency

Xin Huang, Nazym Bashkenova, Yantao Hong, Cong Lyu, Diana Guallar, Zhe Hu, Vikas Malik, Dan Li, Hailin Wang, Xiaohua Shen, Hongwei Zhou, Jianlong Wang

This study identifies a TET1-PSPC1-Neat1 molecular axis that modulates PRC2 binding to chromatin and bivalent gene transcripts during stem cell state transitions.

Cell Reports · Jun 1, 2022Peer-reviewedDevelopmental Biology