Romain Amyot

This study uses HS-AFM to show yeast TOM complexes predominantly form trimers that dynamically dissociate into dimers and monomers, revealing structural and dynamic features of the TOM complex.

The paper introduces A3, a software platform for automated analysis of HS-AFM imaging data, enabling high-throughput quantitative analysis of biomolecular dynamics.

This study shows that coiled-coil kinking in laminin-332 directs elastase cleavage to a specific hinge site, ensuring proper fragment generation, while extended conformations lead to random cleavage and degradation.

The paper introduces NMFF-AFM, a method to infer atomistic models of biomolecular dynamics from HS-AFM imaging data, and integrates it into BioAFMviewer for analysis and visualization.