Author

Clemens M. Franz

Kanazawa UniversityORCID 0000-0003-0104-4841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Holger FlechsigiD· 2 shared Romain AmyotiD· 2 shared Andrew ShevchukiD· 1 shared Carsten BetaiD· 1 shared Hiroki KonnoiD· 1 shared Lucky AkteriD· 1 shared Robert GroßmanniD· 1 shared Soma Yamamoto· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

Holger FlechsigORCID

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3 papers

Recent·Most cited

BioAFMviewer AFM Analysis Arena A3 - an interactive software platform for automated analysis of HS-AFM imaging

Romain Amyot, Soma Yamamoto, Hiroki Konno, Clemens M. Franz, Holger Flechsig

The paper introduces A3, a software platform for automated analysis of HS-AFM imaging data, enabling high-throughput quantitative analysis of biomolecular dynamics.

bioRxiv · Sep 24, 2026 · PreprintBiophysics

Coiled-coil domain kinking controls laminin-332 cleavage by elastase

Lucky Akter, Romain Amyot, Robert Großmann, Carsten Beta, Holger Flechsig, Clemens M. Franz

This study shows that coiled-coil kinking in laminin-332 directs elastase cleavage to a specific hinge site, ensuring proper fragment generation, while extended conformations lead to random cleavage and degradation.

Journal of Molecular Biology · Aug 14, 2026Peer-reviewedCell Biology

Investigating nanostructure and -mechanics of contracting actin stress fibers by scanning ion conductance microscopy

Yanjun Zhang, Yasufumi Takahashi, You-Rong Lin, Andrew Shevchuk, Yuri E. Korchev, Clemens M. Franz

This study uses SICM and cell de-roofing to analyze the nanotopography and mechanics of actin stress fibers during contraction in U2OS cells.

bioRxiv · Jul 7, 2026 · PreprintBiophysics