Noriyuki Kodera

This study uses HS-AFM to show yeast TOM complexes predominantly form trimers that dynamically dissociate into dimers and monomers, revealing structural and dynamic features of the TOM complex.

This study shows the RIG-I 2CARD acts as both a signaling module and a brake on dsRNA translocation using high-speed atomic force microscopy.

This study uses high-speed atomic force microscopy to visualize the dynamics of the Smc5/6 complex interacting with DNA at submolecular resolution, revealing its DNA binding mechanisms.

This study uses HS-AFM to show how RNA folding leads to condensate assembly and distinct material states at the nanoscale.

This study uses high-speed AFM and 3D force mapping to analyze the structural dynamics and nanomechanical properties of dengue virus particles across maturation states.

This study reveals the structural mechanism of MyD88 oligomerization in innate immune signaling using cryo-EM and high-speed AFM.

This study investigates how actin monomers affect XCAP1's interaction with actin filaments using high-speed atomic force microscopy, revealing differences in binding dynamics and preferences.

This study shows that CaMKII holoenzymes form worm-like mesoscale clusters under spatial confinement, with activation leading to cluster expansion and a mutant variant forming clusters even without activation.

The paper uses high-speed AFM to show that CaMKII/{beta} heterododecamers form stable structures with adjacent CaMKII{beta} subunits, revealing their structural role.

This study uses HS-AFM and MD simulations to show that T7 bacteriophage tail fibers have flexible regions enabling dynamic host recognition and surface exploration.

This study shows that myosin V can perform ATP-free walking by converting strain energy from actin binding into mechanical work, similar to ATP-dependent walking.

The paper introduces NMFF-AFM, a method to infer atomistic models of biomolecular dynamics from HS-AFM imaging data, and integrates it into BioAFMviewer for analysis and visualization.

The paper uses high-speed AFM to study how ALK inhibitors affect the structure and dynamics of EML4-ALK variants, revealing IDR-mediated plasticity and resistance mechanisms.

This study shows that MDP1 from Mtb induces RNA condensation through its IDR and PTMs, forming globular structures, while E. coli-expressed MDP1 forms chain-like condensates.

This study uses AFM imaging and molecular modeling to investigate how ATP hydrolysis affects the structural changes in yeast condensin.

This study uses HS-AFM to visualize NTD dynamics of GluA2-γ2, showing dimer splitting and its role in synaptic clustering.

The paper investigates how cofilin binds preferentially to actin filaments by analyzing structural differences and their impact on binding and cluster formation.

The paper uses high-speed atomic force microscopy to study activity-dependent structural dynamics of CaMKII in rat, hydra, and C. elegans, revealing species-specific structural changes and phosphatase tolerance in rat CaMKII.

This study elucidates the mechanism of CRISPR-Cas3-mediated DNA degradation in E. coli, showing how EcoCas3 cleaves ssDNA and degrades dsDNA through specific and non-specific interactions with EcoCascade.