Author

Margaret D. Zimmer

Boston Children's HospitalORCID 0000-0002-3317-6569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan Y. L. WongiD· 1 shared Almut S. EiseleiD· 1 shared Amy YuiD· 1 shared Arjun GargiD· 1 shared Boryana PetrovaiD· 1 shared Efrat Ozeri· 1 shared Jeannette R. BrookiD· 1 shared Jérôme TamburiniiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alan Y. L. WongORCID

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1 paper

Recent·Most cited

One-carbon metabolism sustains effector T cell function through cell-surface glycosylation

Peng Wang, Amy Yu, Mohammed Mutaher, Almut S. Eisele, Sarah Mouche, Kaitlyn Hung, Reece Larson, Madeline Gish, Margaret D. Zimmer, Jeannette R. Brook, Miriam McNerney, Lea Hammer, Arjun Garg, Efrat Ozeri, Alan Y. L. Wong, , Naama Kanarek

This study shows folate deprivation impairs CD8+ T cell function by disrupting cell surface glycosylation, and increasing folate uptake enhances T cell anti-tumor activity.

bioRxiv · Oct 7, 2026 · PreprintCell Biology