Author

Miriam McNerney

Broad InstituteORCID 0009-0007-7274-6986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1

Frequent Co-Authors

Marc A. SchwartziD· 2 shared Mohammed MutaheriD· 2 shared Nir HacoheniD· 2 shared Alan Y. L. WongiD· 1 shared Almut S. EiseleiD· 1 shared Amy YuiD· 1 shared Arjun GargiD· 1 shared Arlene H. SharpeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Marc A. SchwartzORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 7, 2026

One-carbon metabolism sustains effector T cell function through cell-surface glycosylation

Peng Wang, Amy Yu, Mohammed Mutaher…·Naama Kanarek

This study shows folate deprivation impairs CD8+ T cell function by disrupting cell surface glycosylation, and increasing folate uptake enhances T cell anti-tumor activity.

DOI 10.64898/2026.10.06.756889

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 17, 2026

Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors

Marc A. Schwartz, Dillon Lue, Mohammed Mutaher…·Nir Hacohen

The paper identifies Trim28 as a regulator of CD8 T cell differentiation in tumors using clonally-resolved CRISPR screens and shows its role in maintaining TCF7+ stem-like cells while impairing effector differentiation.

DOI 10.64898/2026.06.14.732162

humanscRNA-seq

𝕏 PostBluesky