Ramin S. Herati

This study shows that lymphatic remodeling in skin and lymph nodes constrains germinal center size and function to optimize protective antibody responses during viral infection.

HBV vaccine-draining lymph node biopsies tie low antibody titers to reduced, interferon-skewed GNG4+ germinal center T follicular helper cells; public B cell clonotypes did not track response.

This study tracks T cell clonotypes across tissues in a pig-to-human kidney xenotransplantation model, showing coordinated immune responses preceding xenograft rejection.

This study identifies circulating HA+ IgDneg memory B cells after LAIV, finding they differ in transcriptional profiles and functional capacity compared to IIV-elicited cells.

The paper identifies Treg-CD8 T cell interactions in the sentinel lymph node as predictors of melanoma recurrence in Stage II patients.

The paper characterizes antigen-specific CD8+ T cells post-SARS-CoV-2 vaccination and infection using multimodal sequencing, identifying unique biomarkers and clinical predictors.

This study investigates how antibody concentration, staining volume, and cell number affect signal quality in oligo-conjugated antibody single-cell analysis, offering guidelines to reduce background and improve sensitivity.