Author

Zhousheng Xiao

University of Tennessee Health Science CenterORCID 0000-0002-3363-5673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

L. Darryl QuarlesiD· 2 shared Ankit JoshiiD· 1 shared Bing ZhangiD· 1 shared Charles R. FarberiD· 1 shared Cheryl L. Ackert‐BicknelliD· 1 shared Connor J. CooperiD· 1 shared Danny ArendsiD· 1 shared Fuyi XuiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

L. Darryl QuarlesORCID

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Author profile →

2 papers

Recent·Most cited

Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6

Ankit Joshi, Zhousheng Xiao, Shreya Suman, Connor J. Cooper, Khanh Ha, Rupesh Agarwal, James A. Carson, L. Darryl Quarles, Jeremy C. Smith, Madhulika Gupta

The paper designs small-molecule inhibitors of hIL-6 using computational screening and validates one compound's inhibitory effect on IL6-induced STAT3 activity.

Molecules · Jul 10, 2025Peer-reviewedBioinformatics

Genetic dissection of femoral and tibial microarchitecture

Lu Lu, Jinsong Huang, Fuyi Xu, Zhousheng Xiao, Jing Wang, Bing Zhang, Nicolae Valentin David, Danny Arends, Weikuan Gu, Cheryl L. Ackert‐Bicknell, Olivia L. Sabik, Charles R. Farber, L. Darryl Quarles, Robert W. Williams

The paper uses high-resolution imaging and QTL analysis to study genetic control of bone microarchitecture in mice, identifying 50 candidate genes with potential roles in bone biology.

JBMR Plus · Oct 3, 2019Peer-reviewedGenetics