Author

Manoj K. Mishra

University of ArizonaORCID 0000-0002-3402-388XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Allen W. CowleyiD· 3 shared Andrew Seth GreeneiD· 3 shared Aron M. GeurtsiD· 3 shared Mingyu LiangiD· 3 shared Qiongzi QiuiD· 3 shared Rajan PandeyiD· 3 shared Sridhar RaoiD· 3 shared Bhavika TheraniiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Allen W. CowleyORCID

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3 papers

Recent·Most cited

Chromatin interaction maps of human arterioles reveal new mechanisms for the genetic regulation of blood pressure

Yong Liu, Rajan Pandey, Qiongzi Qiu, Pengyuan Liu, Hong Xue, Jingli Wang, Bhavika Therani, Rong Ying, Kristie Usa, Michael N. Grzybowski, Chun Yang, Manoj K. Mishra, Andrew Seth Greene, Allen W. Cowley, Sridhar Rao, , Mingyu Liang

The paper maps chromatin interactions in human arterioles, linking genetic variants to gene expression and hypertension mechanisms.

Nature Communications · Jul 17, 2025Peer-reviewedGenomics

Physiological role and mechanisms of action for a long noncoding haplotype region

Hong Xue, Manoj K. Mishra, Yong U. Liu, Pengyuan Liu, Michael N. Grzybowski, Rajan Pandey, Kristie Usa, Mark A. Vanden Avond, Niharika Bala, Abdel A. Alli, Allen W. Cowley, Qiongzi Qiu, Andrew Seth Greene, Sridhar Rao, Caitlin Claire O'Meara, , Mingyu Liang

The paper investigates the physiological role and mechanisms of a noncoding haplotype associated with blood pressure by combining animal models, genome editing, and chromatin analysis.

Cell Reports · Jun 1, 2025Peer-reviewedGenetics

Global and genetic regulation of gene expression in human endothelial and vascular smooth muscle cells

Pengyuan Liu, Atrayee Ray, Yong Liu, Manoj K. Mishra, Qiongzi Qiu, Rajan Pandey, Bhavika Therani, Jing Huang, Jiayi Ren, Cary T. Stelloh, Xiaowen Bai, Andrew Seth Greene, Allen W. Cowley, Aron M. Geurts, Sridhar Rao, Mingyu Liang

The paper maps epigenetic and genetic regulation in human endothelial and vascular smooth muscle cells, showing strong correlations between gene expression and chromatin features, and demonstrates SNP effects on gene expression through chromatin loops.

bioRxiv · Dec 25, 2024 · PreprintGenomics