Qiongzi Qiu

This study maps the molecular landscape of hypertension using single-cell data from multiple organs and models, linking genetic variants to disease mechanisms.

This paper shows that PFAS exposure causes salt-sensitive hypertension and kidney injury in mice by increasing ENaC activity in the kidney.

The paper maps chromatin interactions in human arterioles, linking genetic variants to gene expression and hypertension mechanisms.

The paper investigates the physiological role and mechanisms of a noncoding haplotype associated with blood pressure by combining animal models, genome editing, and chromatin analysis.

The paper maps epigenetic and genetic regulation in human endothelial and vascular smooth muscle cells, showing strong correlations between gene expression and chromatin features, and demonstrates SNP effects on gene expression through chromatin loops.