Author

David Datzkiw

University of OttawaORCID 0000-0002-3421-5128Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Ehsan JavandoostiD· 2 shared Fan XiaoiD· 2 shared Michael A. RudnickiiD· 2 shared Uxía Gurriarán‐RodrígueziD· 2 shared Adriana Lucely RojasiD· 1 shared Aitor HierroiD· 1 shared Alberto MarinaiD· 1 shared Félix ElortzaiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenetics

Ehsan JavandoostORCID

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2 papers

Recent·Most cited

GeneticsSkeletal MusclePeer-reviewedDec 19, 2024

Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle

Uxía Gurriarán‐Rodríguez, Kasun Kodippili, David Datzkiw…·Michael A. Rudnicki

This study shows that Wnt7a is critical for muscle regeneration in dystrophic mice, and systemic delivery of Wnt7a-containing extracellular vesicles can rescue regeneration deficits.

12 citations

mouseexperimental assay

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Molecular BiologyScience AdvancesPeer-reviewedDec 11, 2024

Wnt binding to Coatomer proteins directs secretion on exosomes independently of palmitoylation

Uxía Gurriarán‐Rodríguez, David Datzkiw, Leandro Radusky…·Michael A. Rudnicki

This study identifies the structural mechanism by which Wnt7a binds to exosomes for secretion, showing it is independent of palmitoylation and involves a dilysine motif interacting with COPB2.

19 citations

humanproteomics

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