Author

Ehsan Javandoost

University of OttawaORCID 0000-0002-6509-1623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

David DatzkiwiD· 2 shared Fan XiaoiD· 2 shared Michael A. RudnickiiD· 2 shared Uxía Gurriarán‐RodrígueziD· 2 shared Adriana Lucely RojasiD· 1 shared Aitor HierroiD· 1 shared Alberto MarinaiD· 1 shared Félix ElortzaiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenetics

David DatzkiwORCID

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2 papers

Recent·Most cited

Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle

Uxía Gurriarán‐Rodríguez, Kasun Kodippili, David Datzkiw, Ehsan Javandoost, Fan Xiao, María Teresa Rejas, Michael A. Rudnicki

This study shows that Wnt7a is critical for muscle regeneration in dystrophic mice, and systemic delivery of Wnt7a-containing extracellular vesicles can rescue regeneration deficits.

Skeletal Muscle · Dec 19, 2024Peer-reviewedGenetics

Wnt binding to Coatomer proteins directs secretion on exosomes independently of palmitoylation

Uxía Gurriarán‐Rodríguez, David Datzkiw, Leandro Radusky, Marie E. Esper, Ehsan Javandoost, Fan Xiao, Ming Hong, Solomon Fisher, Alberto Marina, Yves De Repentigny, Rashmi Kothary, Mikel Azkargorta, Félix Elortza, Adriana Lucely Rojas, Luis G. Serrano, , Michael A. Rudnicki

This study identifies the structural mechanism by which Wnt7a binds to exosomes for secretion, showing it is independent of palmitoylation and involves a dilysine motif interacting with COPB2.

Science Advances · Dec 11, 2024Peer-reviewedMolecular Biology