Author

Karen M. Park

Columbia UniversityORCID 0000-0002-3433-0601Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro ToboniD· 1 shared Amy R. ReileiniD· 1 shared Andrew Ahern· 1 shared Annique ClaringbouldiD· 1 shared Antonio AdamoiD· 1 shared Christian ArnoldiD· 1 shared Daniel KalderoniD· 1 shared Daria BuninaiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Alejandro TobonORCID

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2 papers

Recent·Most cited

Adult Stem Cells and Niche Cells segregate gradually from common precursors that build the adult Drosophila ovary during pupal development

Amy R. Reilein, Helen V. Kogan, Rachel Misner, Karen Sophia Park, Daniel Kalderon

The paper shows that adult stem cells and niche cells in Drosophila develop from common precursors during pupal stages, with progeny including multiple cell types.

eLife · Sep 30, 2021Peer-reviewedDevelopmental Biology

Pathological LSD1 mutations repress enhancer-mediated gene regulatory networks in early differentiation

Daria Bunina, Pierre‐Luc Germain, Alejandro Tobon, Nadine Fernandez-Novel Marx, Christian Arnold, Andrew Ahern, Annique Claringbould, Mang Ching Lai, Sampathkumar Rangasamy, Vinodh Narayanan, Peter Lorentzen, Karen M. Park, Antonio Adamo, Giuseppe Testa, Judith B. Zaugg, Kyung‐Min Noh

The paper identifies gene regulatory network disruptions caused by LSD1 mutations in early differentiation, showing impaired transcription factor activity and potential therapeutic targets through HDAC inhibition.

bioRxiv · Aug 11, 2021 · PreprintGenomics