Author

Yingying Zhang

Boston Children's HospitalORCID 0000-0002-3435-1330Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yingying Zhang2 papers · BGI Research, Sanya

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aaron BurberryiD· 1 shared Ajitanuj RattaniD· 1 shared Alexander Couto· 1 shared Barbara J. CaldaroneiD· 1 shared Beth StevensiD· 1 shared Brian J. JosephiD· 1 shared Brianna R. WatsoniD· 1 shared Daniel A. MordesiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Aaron BurberryORCID

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2 papers

Recent·Most cited

Single-nucleus sequencing reveals enriched expression of genetic risk factors in Extratelencephalic Neurons sensitive to degeneration in ALS

Francesco Limone, Daniel A. Mordes, Alexander Couto, Brian J. Joseph, Jana M. Mitchell, Martine Therrien, Sulagna Dia Ghosh, Daniel Meyer, Yingying Zhang, Melissa Goldman, Laura Bortolin, Inma Cobos, Beth Stevens, Steven A. McCarroll, Irena Kadiu, , Kevin C. Eggan

The paper identifies cell type-specific molecular changes in ALS patients, showing enrichment of genetic risk factors in extratelencephalic neurons and altered responses in oligodendrocytes and microglia.

Nature Aging · Jun 21, 2024Peer-reviewedNeuroscience

Spatial and temporal profiling of the complement system uncovered novel functions of the alternative complement pathway in brain development

Yingying Zhang, Brianna R. Watson, Ajitanuj Rattan, Tyrone Lee, Smriti Chawla, Ludwig Geistlinger, Yilin Guan, Minghe Ma, Barbara J. Caldarone, Wen‐Chao Song, Jeffrey R. Moffitt, Michael C. Carroll

The paper uses spatial transcriptomics to study complement system development in the brain, revealing distinct roles of the classical and alternative pathways.

bioRxiv · Nov 22, 2023 · PreprintNeuroscience